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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNX1
All Species:
31.52
Human Site:
S423
Identified Species:
69.33
UniProt:
Q01196
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01196
NP_001001890.1
453
48737
S423
N
P
S
L
P
N
Q
S
D
V
V
E
A
E
G
Chimpanzee
Pan troglodytes
XP_531447
467
50347
S437
N
P
S
L
P
N
Q
S
D
V
V
E
A
E
G
Rhesus Macaque
Macaca mulatta
XP_001087338
453
48702
S423
N
P
S
L
P
N
Q
S
D
V
V
E
A
E
G
Dog
Lupus familis
XP_858942
453
48730
S423
N
P
S
L
P
N
Q
S
D
V
V
E
A
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q03347
451
48591
S422
N
P
S
L
P
S
Q
S
D
V
V
E
T
E
G
Rat
Rattus norvegicus
Q63046
450
48538
S421
N
P
S
L
P
S
Q
S
D
V
V
E
T
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989459
472
51671
S442
N
P
N
L
P
N
Q
S
D
G
V
E
A
D
G
Frog
Xenopus laevis
Q6PF39
462
50351
N430
L
L
N
P
N
L
P
N
Q
S
D
V
V
E
A
Zebra Danio
Brachydanio rerio
NP_571678
451
48407
S420
G
S
A
L
L
H
P
S
L
P
N
Q
S
E
G
Tiger Blowfish
Takifugu rubipres
NP_001027815
463
50317
T432
N
P
N
L
P
S
Q
T
E
G
A
V
D
G
D
Fruit Fly
Dros. melanogaster
Q9W349
826
84703
Q679
Q
A
W
S
N
G
Y
Q
N
Y
Q
Y
G
S
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
99.7
98.9
N.A.
95.5
95.3
N.A.
N.A.
65
87.6
72.8
63.7
24.2
N.A.
N.A.
N.A.
Protein Similarity:
100
96.7
100
99.5
N.A.
96.4
96.2
N.A.
N.A.
75.6
91.3
80.5
77.1
32.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
80
6.6
26.6
33.3
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
20
53.3
60
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
0
0
0
10
0
46
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
64
0
10
0
10
10
10
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
64
0
73
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
0
0
0
19
0
0
10
10
73
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
82
10
10
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
73
0
28
0
19
46
0
10
10
0
10
0
0
0
0
% N
% Pro:
0
73
0
10
73
0
19
0
0
10
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
73
10
10
0
10
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
55
10
0
28
0
73
0
10
0
0
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
19
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
55
64
19
10
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _